Journal article
S. A. Marsh, Helen E Collins, J. Chatham
The Journal of Biological Chemistry, 2014
The Journal of Biological Chemistry, 2014
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APA
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Marsh, S. A., Collins, H. E., & Chatham, J. (2014). Protein O-GlcNAcylation and Cardiovascular (Patho)physiology*. The Journal of Biological Chemistry.
Chicago/Turabian
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Marsh, S. A., Helen E Collins, and J. Chatham. “Protein O-GlcNAcylation and Cardiovascular (Patho)Physiology*.” The Journal of Biological Chemistry (2014).
MLA
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Marsh, S. A., et al. “Protein O-GlcNAcylation and Cardiovascular (Patho)Physiology*.” The Journal of Biological Chemistry, 2014.
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@article{s2014a,
title = {Protein O-GlcNAcylation and Cardiovascular (Patho)physiology*},
year = {2014},
journal = {The Journal of Biological Chemistry},
author = {Marsh, S. A. and Collins, Helen E and Chatham, J.}
}
Abstract
Our understanding of the role of protein O-GlcNAcylation in the regulation of the cardiovascular system has increased rapidly in recent years. Studies have linked increased O-GlcNAc levels to glucose toxicity and diabetic complications; conversely, acute activation of O-GlcNAcylation has been shown to be cardioprotective. However, it is also increasingly evident that O-GlcNAc turnover plays a central role in the delicate regulation of the cardiovascular system. Therefore, the goals of this minireview are to summarize our current understanding of how changes in O-GlcNAcylation influence cardiovascular pathophysiology and to highlight the evidence that O-GlcNAc cycling is critical for normal function of the cardiovascular system.